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Updated: Jun 19, 2026

Manufacture and Drug Delivery Applications of Silk Nanoparticles

Manufacture and Drug Delivery Applications of Silk Nanoparticles

Published on: October 8, 2016

Polymer-based nanocapsules for drug delivery.

C E Mora-Huertas¹, H Fessi, A Elaissari

¹Université de Lyon, F-69622, Lyon, France.

International Journal of Pharmaceutics

|October 15, 2009

Summary

This review explores nanocapsules made from preformed polymers for drug delivery. It compares preparation methods and analyzes key characteristics to guide the selection of optimal nanocarrier systems.

Area of Science:

Polymer Science
Nanotechnology
Pharmaceutical Sciences

Background:

Nanocapsules are advanced drug delivery systems utilizing preformed polymers.
Effective drug delivery relies on optimizing nanocarrier properties and preparation methods.

Purpose of the Study:

To review and compare various methods for preparing nanocapsules from preformed polymers.
To analyze critical parameters influencing nanocapsule performance as active substance carriers.

Main Methods:

Systematic review of published research on nanocapsule preparation.
Comparative analysis of methods including nanoprecipitation, emulsion-diffusion, and layer-by-layer.

Main Results:

Detailed comparison of nanocapsule size, zeta-potential, encapsulation efficiency, and drug release profiles.

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Evaluation of in vivo and in vitro pharmacological performance across different preparation techniques.

Conclusions:

Provides criteria for selecting nanocapsule preparation methods based on advantages, limitations, and drug carrier behavior.
Informs the development of tailored nanocapsules for specific therapeutic applications.