Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 19, 2026

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
07:57

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

GPU-based ultrafast IMRT plan optimization.

Chunhua Men1, Xuejun Gu, Dongju Choi

  • 1Department of Radiation Oncology, University of California San Diego, La Jolla, CA 92037, USA.

Physics in Medicine and Biology
|October 15, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SIRT4 Alleviates Retinal Ischemia-Reperfusion Injury Via Mediating Astrocytes Lipid Metabolism and Mitochondrial Function.

Investigative ophthalmology & visual science·2026
Same author

Disrupted brain functional network topology and potential network reorganization in early-stage Parkinson's disease with probable REM sleep behavior disorder.

Neuroscience·2026
Same author

Latent Accelerated Diffusion-based Deformation Estimation for Real-time Volumetric Imaging.

Physics in medicine and biology·2026
Same author

A WEb-Accessible comprehensiVE platform for automatic vestibular schwannoma segmentation and longitudinal volumetric tracking.

Neuro-oncology advances·2026
Same author

From anxiety to innovation: the effect of perceived involution on digital creativity via the parallel mediation of relative deprivation and constructive deviance.

Frontiers in psychology·2026
Same author

Mental health in Kindergarten to Grade 12 schools during the COVID-19 crisis: Literature review and survey suggesting multi-tiered support systems.

Medical research archives·2026
Same journal

Deep learning-based dose prediction to enhance planning efficiency in cervical brachytherapy with hybrid applicators.

Physics in medicine and biology·2026
Same journal

Corrigendum: Referenceless MR thermometry-a comparison of five methods (2017<i>Phys. Med. Biol</i>.<b>62</b>1-16).

Physics in medicine and biology·2026
Same journal

Corrigendum: Measured and Monte Carlo simulated electron backscatter to the monitor chamber for the varian TrueBeam linac (2016<i>Phys. Med. Biol</i>.<b>61</b>8779).

Physics in medicine and biology·2026
Same journal

Corrigendum: 3D range-modulator for scanned particle therapy: development, Monte Carlo simulations and experimental evaluation (2017<i>Phys. Med. Biol</i>.<b>62</b>7075).

Physics in medicine and biology·2026
Same journal

Recent progress in applications of computing to radiotherapy (ICCR 2016).

Physics in medicine and biology·2026
Same journal

Novel TMS coils designed using an inverse boundary element method.

Physics in medicine and biology·2026
See all related articles

Researchers developed a supercomputing online re-planning environment (SCORE) using graphics processing units (GPUs) to accelerate intensity-modulated radiation therapy (IMRT) planning for adaptive radiotherapy, significantly reducing treatment times.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Computational Science

Background:

  • On-board volumetric imaging in cancer radiotherapy necessitates online adaptive techniques to address inter-fraction geometric variations.
  • Real-time treatment planning presents significant technical hurdles for current adaptive radiotherapy approaches.

Purpose of the Study:

  • To implement and evaluate an intensity-modulated radiation therapy (IMRT) optimization algorithm on graphics processing units (GPUs) within a supercomputing online re-planning environment (SCORE).
  • To assess the computational speedup and accuracy of the GPU-accelerated IMRT optimization compared to traditional CPU-based methods.

Main Methods:

  • Development of a penalty-based quadratic optimization model for IMRT.
  • Implementation of the optimization algorithm using CUDA for parallel GPU computing and C for serial CPU computing.

More Related Videos

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Related Experiment Videos

Last Updated: Jun 19, 2026

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
07:57

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

  • Evaluation using a prostate IMRT case with varying beamlet and voxel sizes on an NVIDIA Tesla C1060 GPU.

    • Main Results:

    • Achieved speedup factors of 20-40x on a GPU compared to a CPU, without compromising accuracy.
    • The GPU implementation generated an optimal IMRT plan for a nine-field prostate case in just 2.8 seconds.
    • Demonstrated significant acceleration of IMRT planning suitable for online adaptive radiotherapy.

    Conclusions:

    • The GPU-accelerated IMRT optimization algorithm effectively addresses the real-time planning challenge in adaptive radiotherapy.
    • This SCORE project advancement facilitates the development and clinical implementation of online re-planning technologies.