Related Experiment Video
Updated: Jun 19, 2026

07:11
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
ISCEV standard for clinical visual evoked potentials (2009 update).
J Vernon Odom1, Michael Bach, Mitchell Brigell
1West Virginia University Eye Institute, Morgantown, WV 26506-9193, USA. jodom@wvu.edu
Documenta Ophthalmologica. Advances in Ophthalmology
|October 15, 2009
Summary
This updated standard refines visual evoked potential (VEP) testing parameters for more consistent diagnostic results. Precise VEP protocols aid in evaluating the visual system's functional integrity.
Area of Science:
- Ophthalmology
- Neuroscience
- Clinical Electrophysiology
Background:
- Visual evoked potentials (VEPs) are crucial for assessing visual system function.
- Previous International Society for Clinical Electrophysiology of Vision (ISCEV) standards require updating for improved consistency.
- Clinical electrophysiology laboratories need standardized protocols for reliable VEP testing.
Purpose of the Study:
- To update the ISCEV standard for clinical VEP testing.
- To enhance the precision of VEP test parameters for better inter- and intra-laboratory consistency.
- To provide standardized VEP protocols for assessing prechiasmal visual pathway function.
Main Methods:
- Revision of the 2004 ISCEV standard for clinical VEP testing.
- Definition of precise test parameters for VEP elicitation.
- Specification of core protocols using pattern-reversal, pattern onset/offset, and flash stimuli.
- Recommendation of a single recording channel with a midline occipital electrode for prechiasmal assessment.
Main Results:
- The revised standard introduces more precise test parameters for VEPs.
- Standardized protocols include specific checkerboard sizes for pattern-reversal and onset/offset VEPs (1° and 0.25° checks).
- Flash VEP protocols specify luminance increment stimuli subtending at least 20 degrees.
Conclusions:
- The updated ISCEV standard provides more precise and consistent VEP testing protocols.
- These standardized protocols facilitate reliable assessment of the visual system's functional integrity.
- The defined core protocols are designed for global adoption in clinical electrophysiology labs.

