Related Experiment Video
Updated: Jun 19, 2026

Rating L-DOPA-Induced Dyskinesias in the Unilaterally 6-OHDA-Lesioned Rat Model of Parkinson's Disease
Published on: October 4, 2021
Treatment of tardive dyskinesia with aripiprazole
Ricardo S Osorio1, L Agüera-Ortiz, A Hurtado de Mendoza
1Multidisciplinary Support Unit, Alzheimer's Disease Research Unit, Reina Sofia & CIEN Foundations, Carlos III Institute of Health, Unidad de Investigacion Proyecto Alzheimer, Fundacion Reina Sofia-Fundacion CIEN, c/Valderrebollo 5, Madrid, Spain. rosorio@fundacioncien.es
Abstract:
Tardive dyskinesia (TD) is a severe and potential irreversible side effect of antipsychotic treatment. Treatment of established TD is often unsuccessful. In this article, we report three cases of psychogeriatric patients who suffered from TD as a side effect of long-term treatment with haloperidol that resolved after switching treatment to aripiprazole. Potential psychopharmacological mechanisms explaining this finding are briefly discussed.
Related Concept Videos
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...
Antipsychotic Drugs: Therapeutic Uses and Side Effects
Despite these side effects, antipsychotics are used therapeutically for various purposes, including managing schizophrenia, preventing nausea and vomiting, curbing...
Drug Therapy
Antianxiety Medications
Alzheimer's Disease: Treatment
Psychosis: Goals of Pharmacotherapy
Antipsychotic Drugs: Typical and Atypical Agents
