Related Experiment Video
Updated: Jun 19, 2026

Directed Cellular Self-Assembly to Fabricate Cell-Derived Tissue Rings for Biomechanical Analysis and Tissue Engineering
Published on: November 25, 2011
Development of personalized annuloplasty rings: combination of CT images and CAD-CAM tools
Andrés Díaz Lantada1, Raquel Del Valle-Fernández, Pilar Lafont Morgado
1Grupo de Investigación en Ingeniería de Máquinas, E.T.S.I. Industriales, Universidad Politécnica de Madrid, c/ José Gutiérrez Abascal, no. 2, 28006 Madrid, Spain. adiaz@etsii.upm.es
Abstract:
Although the use of personalized annuloplasty rings manufactured for each patient according to the size and morphology of their valve complex could be beneficial for the treatment of mitral insufficiency, this possibility has been limited for reasons of time-lines and costs as well as for design and manufacturing difficulties, as has been the case with other personalized implant and prosthetic developments. However, the present quality of medical image capture equipment together with the benefits to be had from computer-aided design and manufacturing technologies (CAD-CAM) and the capabilities furnished by rapid prototyping technologies, present new opportunities for a personalized response to the development of implants and prostheses, the social impact of which could turn out to be highly positive. This paper sets out a personalized development of an annuloplasty ring based on the combined use of information from medical imaging, from CAD-CAM design programs and prototype manufacture using rapid prototyping technologies.

