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Updated: Jun 19, 2026

Flow Cytometry Analysis of Tissue Factor Expression in Human Platelets
Published on: November 22, 2024
Platelet-activating factor interaction with the human erythrocyte membrane
Lucyna Mrówczyńska1, Henry Hägerstrand
1Department of Cell Biology, A.Mickiewicz University, PL-61614, Poznań, Poland. lumro@amu.edu.pl
Abstract:
Platelet-activating factor (PAF) is a soluble signal messenger present in blood at nanomolar concentration. PAF has a wide spectrum of biological activities and is produced by and effective in different cell types. Owing to its important physiological role, we wanted to characterize membrane intercalation and interaction of PAF-16 (1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine) by studying its capacity to induce during short-term incubations at high concentrations cell shape alterations, phosphatidylserine exposure, and hemolysis in human erythrocytes. Our results showed that PAF-16 at micromolar concentrations rapidly (
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