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Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder
Published on: September 6, 2024
How early do parent concerns predict later autism diagnosis?
Sally Ozonoff1, Gregory S Young, Mary Beth Steinfeld
1M.I.N.D. Institute, University of California Davis Health System, Sacramento, CA 95817, USA. sally.ozonoff@ucdmc.ucdavis.edu
Journal of Developmental and Behavioral Pediatrics : JDBP
|October 16, 2009
Summary
Parental concerns about developmental milestones by 12 months can predict autism spectrum disorder (ASD) diagnosis. Early identification through parental feedback aids in timely intervention and surveillance for at-risk infants.
Area of Science:
- Developmental Pediatrics
- Autism Spectrum Disorder Research
- Child Psychology
Background:
- Parental concerns regarding child development are crucial indicators.
- Early identification of developmental delays can significantly impact intervention outcomes.
- Autism Spectrum Disorder (ASD) diagnosis relies on behavioral and developmental assessments.
Purpose of the Study:
- To investigate the link between parental concerns about infant development and later ASD diagnostic outcomes.
- To determine the predictive value of parental concerns in the first 18 months of life for ASD diagnosis.
- To assess the utility of parental feedback in identifying infants requiring closer developmental monitoring.
Main Methods:
- Prospective, longitudinal study design tracking infants at high and low risk for ASD.
- Collection of parental developmental concerns at infant ages 6, 12, and 18 months.
- Diagnostic assessment for ASD conducted at 36 months of age.
Main Results:
- Parents of children later diagnosed with ASD reported significantly more autism-related concerns by 12 months.
- Parental concerns at 12 months correlated with developmental status and autism symptoms, predicting later ASD diagnosis.
- Parental concerns at 6 months showed limited predictive value for ASD outcome.
Conclusions:
- Probing parental concerns about development is a valuable tool for early identification of children needing enhanced surveillance.
- Parental insights can supplement clinical assessments in identifying infants at risk for ASD.
- Findings support the American Academy of Pediatrics' recommendations for developmental monitoring.
Related Concept Videos
Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Attention-Deficit/Hyperactivity Disorder
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Oppositional Defiant Disorder
A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
Diagnostic Criteria and...
