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Related Concept Videos

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Regulation of Hematopoietic Stem Cells01:01

Regulation of Hematopoietic Stem Cells

All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...

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Related Experiment Video

Updated: Jun 19, 2026

Ex Vivo Expansion of Hematopoietic Stem Cells from Human Umbilical Cord Blood-derived CD34+ Cells Using Valproic Acid
10:42

Ex Vivo Expansion of Hematopoietic Stem Cells from Human Umbilical Cord Blood-derived CD34+ Cells Using Valproic Acid

Published on: April 11, 2019

[Cord blood banking].

Branka Golubić Cepulić1, Ines Bojanić, Sanja Mazić

  • 1Zavod za transfuziologiju, Klinicki bolnicki centar Zagreb, Zagreb, Hrvatska. bgolubic@kbc-zagreb.hr

Acta Medica Croatica : Casopis Hravatske Akademije Medicinskih Znanosti
|October 16, 2009
PubMed
Summary

Cord blood stem cell transplantation is a growing field for treating various diseases and in regenerative medicine. Establishing diverse cord blood banks is crucial for finding compatible donors and addressing scientific, legal, and ethical considerations.

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Isolation of Endothelial Progenitor Cells from Human Umbilical Cord Blood
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Isolation of Endothelial Progenitor Cells from Human Umbilical Cord Blood

Published on: September 14, 2017

Related Experiment Videos

Last Updated: Jun 19, 2026

Ex Vivo Expansion of Hematopoietic Stem Cells from Human Umbilical Cord Blood-derived CD34+ Cells Using Valproic Acid
10:42

Ex Vivo Expansion of Hematopoietic Stem Cells from Human Umbilical Cord Blood-derived CD34+ Cells Using Valproic Acid

Published on: April 11, 2019

Pan-myeloid Differentiation of Human Cord Blood Derived CD34+ Hematopoietic Stem and Progenitor Cells
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Pan-myeloid Differentiation of Human Cord Blood Derived CD34+ Hematopoietic Stem and Progenitor Cells

Published on: August 9, 2019

Isolation of Endothelial Progenitor Cells from Human Umbilical Cord Blood
07:26

Isolation of Endothelial Progenitor Cells from Human Umbilical Cord Blood

Published on: September 14, 2017

Area of Science:

  • Hematology
  • Regenerative Medicine
  • Immunology

Context:

  • Cord blood stem cells offer therapeutic potential for hematologic malignancies, immune deficiencies, and metabolic disorders.
  • Emerging applications include regenerative medicine for neurodegenerative and cardiovascular diseases.
  • Growing interest in cord blood banking necessitates a diverse inventory of stem cells for donor matching.

Purpose:

  • To review the current applications and expanding role of cord blood stem cells in medicine.
  • To highlight the importance of cord blood banking for future therapeutic needs.
  • To discuss the scientific, legal, ethical, and political issues surrounding cord blood banking.

Summary:

  • Cord blood stem cell transplantation is a rapidly advancing therapeutic option.
  • Cord blood banking is essential for creating a genetically diverse cell stock for transplantation.
  • Public and private cord blood banks facilitate unrelated and family-directed donations, respectively.

Impact:

  • Facilitates the development of new treatments for a range of diseases.
  • Enhances the availability of compatible hematopoietic stem cell transplants.
  • Addresses the complex challenges associated with establishing and managing cord blood banks.