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A case of maternity testing: exclusion by polymorphic VNTR markers of DNA
A Akane1, H Nakajima, H Shiono
1Department of Legal Medicine, Shimane Medical University, Izuma, Japan.
Jinrui Idengaku Zasshi. the Japanese Journal of Human Genetics
|December 1, 1990
Abstract:
The genetic markers of a Korean woman and her allegedly adopted child were compared to test her maternity. None of 21 conventional markers, including 8 red cell antigens, 6 red cell enzymes, and 7 serum proteins, excluded the maternity. These results indicate a maternal probability of 0.31 which was too low to conclude the true maternity. Human leukocyte antigen (HLA)-A, -B, -C and -DR haplotyping was also uninformative in this case. The maternity was consequently excluded by the observation of a difference in 2 of 5 variable number of tandem repeat (VNTR) markers.