Related Experiment Video
Updated: Jun 19, 2026

A Rapidly Incremented Tethered-Swimming Maximal Protocol for Cardiorespiratory Assessment of Swimmers
Published on: January 28, 2020
Circulating T-regulatory cells, exercise and the elite adolescent swimmer
Lori D Wilson1, Frank P Zaldivar, Christina D Schwindt
1Pediatric Exercise Research Center, Department of Pediatrics, University Children's Hospital, University of California, Irvine, CA 92868, USA.
Abstract:
Brief high intensity exercise induces peripheral leukocytosis possibly leading to a higher incidence of allergic symptoms in athletes undergoing excessive training. We studied the exercise-induced alternation of circulating Tregs and FoxP3+ Tregs due to acute intense swim exercise in elite swimmers (n = 22, 12 males, age = 15.4 yrs). Twelve had prior or current rhinitis or asthma and 10 had no current or prior allergy or asthma. Circulating Tregs increased significantly (p < .001) following exercise (pre = 133 +/- 11.2, post = 196 +/- 17.6) as did FoxP3+ cells (pre = 44, post = 64 cells/microl). Increases in Tregs and FoxP3+ Tregs occurred to the same extent in both groups of adolescent swimmers.
Related Concept Videos
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be met...
Regulation of Hematopoietic Stem Cells
T Cell Types and Functions
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Cellular Adaptation II: Hypertrophy
T Cell Activation and Clonal Selection
Naive T cells that have not yet encountered an antigen express two primary CD...
Cells of the Adaptive Immune Response

