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Remarks on reporting and recording consistent with the ICRU reference dose.

Klaus Bratengeier1, Markus Oechsner, Mark Gainey

  • 1Klinik und Poliklinik für Strahlentherapie, University of Würzburg Josef-Schneider-Str, 11, 97080 Würzburg, Germany. Bratengeier_K@klinik.uni-wuerzburg.de

Radiation Oncology (London, England)
|October 16, 2009
PubMed
Summary
This summary is machine-generated.

For Intensity Modulated Radiotherapy (IMRT), reporting the planning target volume (PTV) median dose or PTVx mean dose offers a consistent alternative to the ICRU Reference Dose for improved radiotherapy reporting.

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Area of Science:

  • Radiation Oncology
  • Medical Physics
  • Radiotherapy Planning

Background:

  • ICRU 50/62 provides a framework for external beam radiotherapy reporting.
  • Current methods struggle to define a characteristic PTV dose for Intensity Modulated Radiotherapy (IMRT).
  • Volume-based dose reporting methods are increasingly used for IMRT.

Purpose of the Study:

  • To compare the usability and compatibility of different volume-based dose reporting methods for IMRT.
  • To evaluate these methods against the ICRU Reference Point dose for conformal radiotherapy (CRT).

Main Methods:

  • Compared dose distributions from 45 CRT and 57 IMRT plans.
  • Evaluated mean, median, and D95 doses for the planning target volume (PTV) and its central part (PTVx).
  • Assessed correlation between methods and effects of boluses and simultaneous integrated boosts (SIB).

Main Results:

  • PTV median dose and PTVx mean dose showed high consistency with ICRU reporting.
  • PTVx mean dose approximates CTV mean dose in specific scenarios.
  • CTV mean dose reporting may overestimate plateau doses in SIB plans.

Conclusions:

  • Advocate for PTV median dose or PTVx mean dose as replacements for ICRU Reference Dose.
  • These proposed methods are suitable for both CRT and IMRT.
  • PTVx allows for better approximation of biological effects via dose standard deviation.