Influenza activity in Cambodia during 2006-2008
Sek Mardy1, Sovann Ly, Seng Heng
1Institut Pasteur in Cambodia, 5 Monivong Blvd, Phnom Penh, Cambodia. mardy@pasteur-kh.org
BMC Infectious Diseases
|October 16, 2009
Summary
Influenza circulates in Cambodia from June to December, peaking in October, primarily during the rainy season. This pattern allows for improved influenza vaccination recommendations for the region.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- Limited data existed on influenza disease in Cambodia.
- The Cambodian National Influenza Center (NIC) was established in 2006.
- Hospital-based surveillance for influenza-like illness (ILI) and acute lower respiratory infection (ALRI) was initiated.
Purpose of the Study:
- To understand influenza dynamics in Cambodia.
- To establish a system for continuous influenza monitoring.
- To inform influenza vaccination strategies.
Main Methods:
- Weekly collection of epidemiological data and nasopharyngeal specimens from ILI cases.
- Multiplex RT-PCR for simultaneous detection of influenza A and B viruses.
- Hemagglutination inhibition assay for influenza A subtyping and antigenic analysis.
Main Results:
- Influenza circulation was observed from June to December between 2006 and 2008.
- A distinct seasonal peak occurred in October, particularly in 2008.
- Surveillance data revealed a consistent pattern of influenza activity.
Conclusions:
- Influenza activity in Cambodia coincides with the rainy season (June-December).
- The transmission pattern resembles that of the southern hemisphere, despite Cambodia's location.
- Findings support tailored influenza vaccination recommendations for Cambodia.
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