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Updated: Jun 19, 2026

A Murine Closed-chest Model of Myocardial Ischemia and Reperfusion

A Murine Closed-chest Model of Myocardial Ischemia and Reperfusion

Published on: July 17, 2012

Intraoperative stress cardiomyopathy.

Edward Gologorsky¹, Angela Gologorsky

¹Department of Anesthesiology, CVT Division, University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, Florida 33136, USA. egologorsky@med.miami.edu

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography

|October 16, 2009

Summary

This case report highlights how transesophageal echocardiography aids in diagnosing intraoperative tako-tsubo cardiomyopathy, a form of stress cardiomyopathy, during surgery. Early diagnosis using this imaging technique is crucial for managing sudden hypotension and pulmonary edema.

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Last Updated: Jun 19, 2026

A Murine Closed-chest Model of Myocardial Ischemia and Reperfusion

A Murine Closed-chest Model of Myocardial Ischemia and Reperfusion

Published on: July 17, 2012

Area of Science:

Cardiology
Anesthesiology
Medical Imaging

Background:

Intraoperative hypotension and pulmonary edema can mimic acute coronary syndromes.
Tako-tsubo cardiomyopathy (stress-induced cardiomyopathy) is a potential cause of these intraoperative complications.
Transesophageal echocardiography (TEE) is an advanced imaging modality used during surgery.

Observation:

A female patient under general anesthesia developed sudden hypotension and mild pulmonary edema during surgery.
Transesophageal echocardiography was immediately performed to investigate the cause.
The echocardiographic findings suggested stress-induced cardiomyopathy.

Findings:

The suspected diagnosis of intraoperative tako-tsubo cardiomyopathy was confirmed by computed tomographic angiography and cardiac catheterization.
Transesophageal echocardiography proved vital in the rapid differential diagnosis.
The patient experienced a full recovery.

Implications:

This case underscores the critical role of transesophageal echocardiography in diagnosing intraoperative cardiovascular emergencies.
TEE facilitates the differentiation between stress cardiomyopathy and acute coronary syndrome during surgery.
Prompt diagnosis and management improve patient outcomes in intraoperative hypotension scenarios.