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Updated: Jun 19, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
Published on: March 21, 2013
High prevalence of orthostatic hypotension in mild dementia
Hogne Sonnesyn1, Dennis W Nilsen, Arvid Rongve
1Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway. soho@sus.no
Background/Aims:
Orthostatic hypotension (OH) and QTc prolongation have potentially important prognostic and therapeutic consequences but have rarely been studied in patients with mild dementia.
Methods:
Patients with mild dementia were diagnosed according to consensus criteria after comprehensive standardized assessment. OH and QTc were assessed using standardized criteria.
Results:
OH was significantly more common in the dementia than in the control group, and systolic drop was higher in those with dementia with Lewy bodies. There were no significant differences in QTc values between dementia and control subjects.
Conclusion:
OH occurs even in patients with mild dementia, in particular in dementia with Lewy bodies. QTc was not prolonged in patients with mild dementia compared with normal controls.
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