Related Experiment Videos
Some pharmacological properties of perhydro-1,4-thiazepine and perhydro-1,2,5-dithiazepine derivatives
M Strzelczyk1, H Matyjewska, H Strózyński
1Department of Biochemistry, Pharmacology and Biology, Military Medical Academy, Lódź, Poland.
Polish Journal of Pharmacology and Pharmacy
|July 1, 1990
Abstract:
Some newly synthesized perhydro-1,2,5-dithiazepine derivatives have antihistaminic, anticholinergic and spasmolytic properties. One perhydro-1,4-thiazepine derivative, compound 3, produces also a weak local anesthetic effect. The activity of the investigated compounds is lower than that of reference compounds; diphenhydramine, antazoline and papaverine.