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Transient left ventricular dysfunction in Churg Strauss syndrome: a case report
Ioannis Vlahodimitris1, Maria Christina Kyrtsonis, Nikolaos Lionakis
1Cardiac Department, Laiko General Hospital of Athens, 17 Agiou Thomas St. GR-15727 Goudi, Athens, Greece. yiannisvlahodimitris@yahoo.gr
Cases Journal
|October 16, 2009
Summary
Churg Strauss Syndrome can cause heart problems like left ventricular dysfunction. Cardiac MRI aids in early detection of myocardial damage, and corticosteroid treatment can improve heart function.
Area of Science:
- Cardiology
- Immunology
- Radiology
Background:
- Churg Strauss Syndrome (CSS), also known as eosinophilic granulomatosis with polyangiitis, is a rare systemic vasculitis.
- Myocardial involvement in CSS can lead to significant cardiac dysfunction.
- Early diagnosis and management are crucial for improving patient outcomes.
Observation:
- A 42-year-old woman presented with eosinophilia and cardiac abnormalities.
- Echocardiography revealed left ventricular dysfunction (ejection fraction 45%) and mild pericardial effusion.
- Cardiac Magnetic Resonance (CMR) imaging was performed for detailed assessment.
Findings:
- T2-weighted CMR images showed myocardial edema in the interventricular septum.
- Delayed gadolinium-enhanced CMR images indicated myocardial fibrosis in the same region.
- Methylprednisolone therapy was initiated for suspected CSS-related myocardial involvement.
Implications:
- CMR is a valuable tool for detecting and characterizing myocardial damage in CSS.
- Corticosteroid treatment led to significant improvement in left ventricular function.
- This case highlights the importance of cardiac evaluation in patients with CSS.
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