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Primary intraosseous osteolytic meningioma of the skull: a case report
Abdolreza Sheikhrezaie1, Ali Tayebi Meybodi, Mohammad Hashemi
1Department of Neurosurgery, Imam Khomeini Hospital, Tehran University of Medical Sciences Tehran 14197 Iran. dr_sheikhrezaie@yahoo.com
Abstract:
Primary intraosseous meningiomas are uncommon. The osteolytic variants of these tumors are even rarer. When one reviews a bony skull lesion, the differential diagnosis is very wide and includes both malignant and benign diseases. In case of primary skull meningioma, correct diagnosis and total resection of the lesion ensures curative therapy. Presented is a case of osteolytic skull lesion not invading the dura that was proved to be a fibrillary meningioma with regions of syncitial pattern.
Insights
Primary intraosseous meningiomas are rare bone tumors. This case highlights an osteolytic variant, emphasizing accurate diagnosis and surgical resection for effective treatment of skull lesions.
Area of Science:
- Neurosurgery
- Oncology
- Pathology
Background:
- Primary intraosseous meningiomas are rare tumors arising within bone, distinct from intracranial meningiomas.
- Osteolytic variants, characterized by bone destruction, represent an even rarer subtype, posing diagnostic challenges.
- Skull lesions have a broad differential diagnosis, necessitating careful evaluation to distinguish benign from malignant conditions.
Observation:
- A case of an osteolytic skull lesion was investigated.
- The lesion did not demonstrate invasion of the dura mater.
- Histopathological examination revealed a fibrillary meningioma with areas exhibiting a syncitial pattern.
Findings:
- The presented case is an exceptionally rare osteolytic primary intraosseous meningioma.
- The tumor was histologically classified as a fibrillary meningioma with syncitial features.
- The lesion was confined to the bone without dural invasion.
Implications:
- Accurate diagnosis of osteolytic skull lesions is crucial for appropriate management.
- Total surgical resection is curative for primary skull meningiomas.
- Understanding rare variants like osteolytic intraosseous meningiomas expands the differential diagnosis for bony skull lesions.
