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Related Experiment Video

Updated: Jun 19, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia

Inducement and Evaluation of a Murine Model of Experimental Myopia

Published on: January 22, 2019

Topiramate induced acute transient myopia: a case report.

Sandra D Gawley¹

¹St Paul's Eye Unit, The Royal Liverpool University Hospital Prescot Street, Liverpool, Merseyside UK. sandragawley@hotmail.com

|October 16, 2009

Summary

Topiramate, used for epilepsy and migraine, can cause sudden acute myopia. This rare side effect resolves upon drug discontinuation, highlighting the need for ophthalmologist awareness.

Area of Science:

Ophthalmology
Neurology

Background:

Topiramate is a widely prescribed anticonvulsant and migraine prophylactic.
Its therapeutic benefits are well-established in epilepsy and migraine management.

Observation:

A case study details a 34-year-old female experiencing sudden blurred vision.
This occurred 9 days after initiating topiramate for migraine prophylaxis.

Findings:

The patient presented with significantly reduced visual acuity (6/36 OD, 2/60 OS).
Ocular examination revealed acute myopia and anatomical changes.
These changes resolved rapidly after discontinuing topiramate therapy.

Implications:

Ophthalmologists must recognize topiramate-induced acute transient myopia.

Related Experiment Videos

Last Updated: Jun 19, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia

Inducement and Evaluation of a Murine Model of Experimental Myopia

Published on: January 22, 2019

Early identification and drug cessation are crucial for prompt visual recovery.

This adverse event underscores the importance of monitoring ocular health during topiramate treatment.