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Collagenous gastritis, a new spectrum of disease in pediatric patients: two case reports

David Suskind1, Ghassan Wahbeh, Karen Murray

  • 1Departments of Pediatrics and 2Laboratories, Children’s Hospital and Regional Medical Center, University of Washington, Seattle,WA, USA. David.suskind@seattlechildrens.org

Cases Journal
|October 16, 2009
PubMed

Insights

Collagenous gastritis, a rare disorder, presents differently in children. This study highlights the first reported pediatric case of the adult-onset form, challenging existing classifications.

Area of Science:

  • Gastroenterology
  • Pediatric Gastroenterology
  • Pathology

Background:

  • Collagenous gastritis is a rare gastrointestinal disease with distinct pediatric and adult phenotypes.
  • Pediatric collagenous gastritis typically presents with abdominal pain and anemia.
  • Adult-onset collagenous gastritis is associated with collagenous colitis and diarrhea.

Observation:

  • This report details two pediatric cases of collagenous gastritis.
  • One case exhibited classic pediatric symptoms.
  • The second case presented with features of adult-onset collagenous gastritis.

Findings:

  • This study reports the first pediatric case of adult-onset collagenous gastritis.
  • The findings suggest potential overlap or a broader spectrum for collagenous gastritis phenotypes.
  • This challenges the strict division between pediatric and adult forms.

Implications:

  • The findings may necessitate a re-evaluation of collagenous gastritis classification in pediatric patients.
  • Recognizing the adult-onset phenotype in children could improve diagnosis and management.
  • Further research is needed to understand the variability and underlying mechanisms of collagenous gastritis.

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