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Uterine adenosarcoma associated to lymphovascular emboli: a case report
Rita Sakr1, Paul Marzouk, Alexandre Bricou
1Department of Gynecology, Hôpital Armand-Trousseau, 75012 Paris, France and 2Department of Pathology, Hôpital Tenon, 75020 Paris, France. rita.sakr@trs.aphp.fr
Cases Journal
|October 16, 2009
Summary
Uterine adenosarcoma, a rare tumor, can be challenging to diagnose, often requiring multiple procedures. This case highlights its association with lymphovascular invasion, impacting patient survival.
Area of Science:
- Gynecologic Oncology
- Pathology
- Surgical Oncology
Background:
- Uterine adenosarcoma is a rare biphasic tumor comprising benign epithelium and malignant stroma.
- Diagnosis can be challenging, often requiring extensive evaluation.
- Standard treatment involves hysterectomy with bilateral salpingo-oophorectomy.
Observation:
- A 45-year-old woman presented with uterine bleeding and recurrent polyps.
- Initial pathology did not reveal malignancy.
- Atypical cells led to total abdominal hysterectomy, confirming uterine adenosarcoma.
Findings:
- The confirmed uterine adenosarcoma exhibited lymphovascular invasion (tumor emboli).
- This finding significantly impacts prognosis and survival rates.
- The case underscores the importance of vigilant diagnosis in suspected adenosarcoma.
Implications:
- Highlights the diagnostic challenges and potential for delayed diagnosis of uterine adenosarcoma.
- Emphasizes the prognostic significance of lymphovascular invasion in uterine adenosarcoma.
- Reinforces the need for comprehensive surgical management including lymphadenectomy in relevant cases.
