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Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

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Nutritional optic and peripheral neuropathy: a case report.

Laura M Nightingale¹, Dominic C Paviour

¹A&E Department, St Thomas’ Hospital, Lambeth Palace Road, London SE1 7EH, UK. laura.nightingale@doctors.org.uk

|October 16, 2009

Summary

A vegan diet may lead to optic and peripheral neuropathy, particularly in individuals with tropical or subtropical climate exposure. This case highlights the importance of nutritional status in preventing neurological conditions.

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Area of Science:

Neurology
Nutritional Science

Background:

Nutritional status is linked to optic and peripheral neuropathies.
Causative factors include tobacco, ethanol, and deficiencies in thiamine, vitamins A, B12, B3, B6, and protein-energy malnutrition.

Observation:

A 32-year-old Afro-Caribbean man of Jamaican origin presented with blurred vision and painful burning feet.
Clinical features indicated both optic and peripheral neuropathy.

Findings:

The patient adhered to a strict vegan diet, consuming no animal products.
The case shares similarities with Strachan's syndrome, characterized by optic and peripheral neuropathy and cutaneous excoriation.

Implications:

This case provides evidence for the association between veganism, nutritional deficiencies, and neurological conditions like Strachan's syndrome.
Previous residence in tropical or subtropical climates may be a contributing factor.