A strange Evans syndrome: a case report
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In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
Published on: August 20, 2019
Julie Le Scanff1, Stéphane Durupt, François Bailly
1Department of Internal Medicine, Hospices Civils de Lyon, Hotel Dieu, 1 place de l’Hôpital, 69288 Lyon Cedex 02, France andUniversity Claude Bernard Lyon 1, Lyon, France. julie.mestrallet@chu-lyon.fr
Abstract:
Hepatic angiosarcoma is a rare malignant vascular tumor, which accounts for up to 2% of all primary liver tumors. The most frequent symptoms on presentation are weight loss, weakness and abdominal pain. Diagnosis of diffuse hepatic angiosarcoma can be challenging. We report an original case of diffuse liver angiosarcoma revealed by haematological abnormalities initially diagnosed as an Evans syndrome. Anaemia and thrombocytopenia are rarely the first manifestations of this pathology. They are explained by combination of several mechanisms. Diagnosis of diffuse liver angiosarcoma can be extremely difficult and physicians should be aware of these presentation.
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