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[Our first experience with allogeneic and autologous transplantation of hematopoietic stem cells]
K Sułek1, M Kłos, Z Dańczak-Ginalska
1V Kliniki Chorob Wewnetrznych Instytutu Med. Wewn. CSK WAM.
The main problems and difficulties in transplantation of haematogenous stem cells are discussed. The problems include: organization of a team of specialists and bone marrow transplantation centre, preparation of the recipient (patient) complications connected with preparation for transplantation, graft taking, graft versus host disease, recurrence of the underlying disease. In the analysis only those patients (8 cases) are included who had received marrow transplantation after chemotherapeutic-radiotherapeutic preparation (3 patients are alive). The first experiences are described also with three autotransplantations of haematogenous stem cells obtained by means of cell separator from peripheral blood. These experiences indicate that it is possible in our country to carry out this highly sophisticated method which requires, however, further improvements and ensuring of adequate personnel and equipment.
The main problems and difficulties in transplantation of haematogenous stem cells are discussed. The problems include: organization of a team of specialists and bone marrow transplantation centre, preparation of the recipient (patient) complications connected with preparation for transplantation, graft taking, graft versus host disease, recurrence of the underlying disease. In the analysis only those patients (8 cases) are included who had received marrow transplantation after chemotherapeutic-radiotherapeutic preparation (3 patients are alive). The first experiences are described also with three autotransplantations of haematogenous stem cells obtained by means of cell separator from peripheral blood. These experiences indicate that it is possible in our country to carry out this highly sophisticated method which requires, however, further improvements and ensuring of adequate personnel and equipment.