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Lattice corneal dystrophy, gelsolin type (Meretoja's syndrome)
Christian Carrwik1, Ulf Stenevi
1Department of Ophthalmology, Sahlgrenska University Hospital, Mölndal, Gothenburg, Sweden.
Acta Ophthalmologica
|October 17, 2009
Summary
Lattice corneal dystrophy, gelsolin type (LCD2), an inherited condition, presents with eye and systemic symptoms. Early diagnosis and symptomatic treatment, including lubrication and pressure monitoring, are key to managing this chronic disease.
Area of Science:
- Ophthalmology
- Genetics
- Corneal Diseases
Background:
- Lattice corneal dystrophy, gelsolin type (LCD2), also known as Meretoja's syndrome, is a rare inherited disorder.
- This review synthesizes current knowledge on its pathogenesis, clinical features, and management.
Observation:
- The condition has been reported globally, including Europe, Japan, the USA, and Iran.
- A case study of a Finnish patient in Sweden and expert interviews informed this review.
Findings:
- Treatment is primarily symptomatic, focusing on ocular lubrication and intraocular pressure management to delay keratoplasty.
- Systemic symptoms necessitate consultation with other medical specialists.
Implications:
- LCD2 is likely under-reported and may be present in more countries, including Sweden.
- Ophthalmologists should maintain vigilance for LCD2, recognizing its inherited, chronic nature and potential systemic involvement.
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