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Updated: Jun 19, 2026

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
Published on: September 16, 2020
Profound retinal ischaemia after ranibizumab administration in an eye with ocular ischaemic syndrome
Peter Kristian Kofoed1, Inger Christine Munch, Michael Larsen
1Department of Ophthalmology, Glostrup Hospital, University of Copenhagen, Denmark. peter.k@dadlnet.dk
Purpose:
To report the result of ranibizumab administration in an eye with ocular ischaemic syndrome.
Methods:
Fluorescein angiography, ocular pneumoplethysmography and retinal vessel calibre measurement.
Results:
An 85-year-old man with ocular ischaemic syndrome demonstrated vision loss, retinal vessel calibre constriction and profound retinal ischaemia after intravitreal ranibizumab.
Conclusion:
We advise against the use of intravitreal vascular endothelial growth factor inhibitors in eyes with ocular ischaemic syndrome.
