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Maternal thyroid function during gestation is related to breech presentation at term.

S M I Kuppens¹, L Kooistra, H A Wijnen

¹Department of Obstetrics and Gynecology, Catharina Hospital, Eindhoven.

Clinical Endocrinology

|October 17, 2009

Summary

This summary is machine-generated.

Suboptimal maternal thyroid function, indicated by elevated thyroid-stimulating hormone (TSH) levels late in pregnancy, is linked to an increased risk of breech presentation. This finding highlights the importance of monitoring maternal thyroid health during gestation.

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Area of Science:

Obstetrics and Gynecology
Endocrinology
Perinatal Medicine

Background:

Breech presentation at term is associated with increased obstetric risks.
Maternal thyroid function can influence fetal positioning.

Purpose of the Study:

To investigate the association between maternal thyroid function during pregnancy and the occurrence of breech presentation at term.

Main Methods:

A prospective follow-up study of 1058 healthy pregnant women was conducted.
Maternal thyroid parameters (TSH, FT4, thyroid peroxidase antibodies) were measured at 12, 24, and 36 weeks gestation.
Fetal presentation at term was recorded.

Main Results:

A significantly higher TSH concentration was observed in women with breech presentation at 36 weeks gestation (P = 0.007).
Women with TSH levels >= 2.5 mIU/l at 36 weeks had an 11% prevalence of breech presentation, compared to 4.8% with lower TSH levels (P = 0.006).
High maternal TSH at 36 weeks was independently related to breech position (OR: 2.23).

Conclusions:

Elevated maternal TSH levels (> or = 2.5 mIU/l) in late gestation are a risk factor for breech presentation.
This association suggests potential implications for obstetric management and outcomes.