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Related Concept Videos

Action Potentials

Action Potentials

Action Potential

Action Potential

Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...

Propagation of Action Potentials

Propagation of Action Potentials

The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...

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Related Experiment Video

Updated: Jun 19, 2026

Extracting Visual Evoked Potentials from EEG Data Recorded During fMRI-guided Transcranial Magnetic Stimulation

Extracting Visual Evoked Potentials from EEG Data Recorded During fMRI-guided Transcranial Magnetic Stimulation

Published on: May 12, 2014

Reducing blanking artifact in electrically evoked compound action potentials.

Isaac Alvarez¹, Angel de la Torre, Manuel Sainz

¹Department of Signal Theory, Telematics and Communications, University of Granada, Granada, Spain. isamaru@ugr.es

Computer Methods and Programs in Biomedicine

|October 17, 2009

Summary

This summary is machine-generated.

This study introduces new methods to reduce artifacts in electrically evoked compound action potential recordings. These techniques improve the clarity and quality of recorded evoked potentials.

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Area of Science:

Neuroscience
Biomedical Engineering
Signal Processing

Background:

Stimulus artifacts are a primary source of distortion in electrically evoked compound action potential (EVCAP) recordings.
Hardware blanking, a common technique to reduce stimulus artifacts, can introduce a secondary blanking artifact due to amplifier transient states.

Purpose of the Study:

To propose and evaluate novel techniques for mitigating blanking artifacts in EVCAP recordings.
To combine these new methods with alternating stimulation strategies to reduce both stimulus and blanking artifacts.

Main Methods:

Development of two novel techniques to address the blanking artifact.
Integration of these techniques with conventional and generalized alternating stimulation protocols.
Comparative analysis of artifact reduction effectiveness across 126 EVCAP recordings.

Main Results:

The proposed techniques effectively reduce blanking artifacts.
Combined approaches significantly decrease both stimulus and blanking artifacts.
Improved signal quality in EVCAP recordings was demonstrated.

Conclusions:

The novel blanking artifact reduction methods enhance the quality of EVCAP recordings.
These techniques offer a valuable improvement for neurophysiological signal acquisition and analysis.