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Updated: Jun 19, 2026

Determination of Vaccine Immunogenicity Using Bovine Monocyte-Derived Dendritic Cells
Published on: May 19, 2023
Epidemiology and control of BVD in the U.S
1Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523-1644, USA. hvancamp@lamar.colostate.edu
Abstract:
The apparent prevalence of bovine viral diarrhea virus (BVDV) persistently infected cattle has been found to be low in U.S. dairies, beef herds and feedlots. Current management practices within U.S. cattle industries that impact the epidemiology of BVDV infections include purchasing untested cattle, lack of biosecurity procedures, large herd sizes, mixing cattle from multiple sources, high cattle densities in dairy and feedlot operations, synchronous breeding of beef herds, communal grazing and widespread vaccination. Evidence for BVDV infection has been found in farmed and free-ranging wildlife in North America; however the risk of BVDV transmission from wildlife to cattle is not known. The perception of a low prevalence of BVDV herd infections, the unrestricted sale of PI cattle, lack of economic data, intensive marketing of vaccines, reluctance to accept federal regulations, and a "gambler's" attitude among producers are impediments to implementation of a national systematic BVD control program. Since 2004, voluntary BVDV control programs have been organized in nine states reflecting the recognition of BVD as an important and preventable problem in the U.S.
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