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Related Concept Videos

Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
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Documentation of Nursing Diagnosis01:10

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Updated: Jun 19, 2026

Improving IV Insulin Administration in a Community Hospital
12:08

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Published on: June 11, 2012

Drug administration error related to computerized prescribing.

P Le Garlantezec1, O Aupée, D Alméras

  • 1Hôpital d'instruction des armées du Val de Grâce, Pharmacy Department, Paris, France. le.garlantezec.pharm@gmail.com

Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners
|October 17, 2009
PubMed
Summary

Computerized prescribing aims to reduce medication errors, but a vincristine administration error occurred due to incorrect programming. Improved protocols and pharmacist/nurse training are crucial for preventing such errors.

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Area of Science:

  • Oncology
  • Pharmacology
  • Patient Safety

Background:

  • Computer-based prescribing systems were implemented to minimize medication errors.
  • Despite advancements, new types of prescribing and administration errors persist.

Observation:

  • A case report details a medication error involving vincristine, an antineoplastic agent.
  • The drug was administered subcutaneously instead of intravenously due to a programming error in the protocol.

Findings:

  • The incorrect administration route led to cutaneous erythema in the patient.
  • The error originated from a programming mistake in the administration route, missed by both the pharmacist and physician.
  • The pharmacist, responsible for order validation, compounding, and dispensing, failed to identify the critical error.

Implications:

  • Highlights the necessity for robust, validated therapeutic protocols within databases to ensure safe computer-based prescribing.
  • Emphasizes the need for enhanced training for nurses and pharmacists to detect novel medication errors and periodically review protocols.