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Colonic sarcoidosis presenting multiple submucosal tumor-like lesions
Atsuhito Ushiki1, Tomonobu Koizumi, Keishi Kubo
1The First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto.
Internal Medicine (Tokyo, Japan)
|October 17, 2009
Summary
Colonic sarcoidosis, a rare condition, can manifest as multiple submucosal tumor-like lesions. This case highlights the importance of considering colonic involvement in patients with sarcoidosis.
Area of Science:
- Gastroenterology
- Pulmonology
- Pathology
Background:
- Sarcoidosis is a multisystem inflammatory disease characterized by noncaseating granulomas.
- Intrathoracic sarcoidosis is the most common form, but extrathoracic involvement can occur.
- Colonic involvement in sarcoidosis is uncommon and often asymptomatic.
Observation:
- A patient with a 7-year history of intrathoracic sarcoidosis presented with asymptomatic colonic lesions.
- Colonoscopy revealed multiple elevated lesions resembling submucosal tumors throughout the colon.
- Biopsies confirmed noncaseating granulomas, indicative of sarcoidosis.
Findings:
- The case demonstrates a rare presentation of colonic sarcoidosis.
- The macroscopic appearance of multiple submucosal tumor-like lesions is highly unusual for colonic sarcoidosis.
- Histopathological examination confirmed sarcoidosis as the cause of the colonic lesions.
Implications:
- Colonic sarcoidosis should be considered in the differential diagnosis of patients with known sarcoidosis, even if asymptomatic.
- The unusual endoscopic findings underscore the need for thorough investigation in suspected cases.
- This case contributes to understanding the diverse clinical manifestations of sarcoidosis.
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