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Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
Stereotactic radiosurgery for cavernous sinus or orbital hemangiomas.
Aftab A Khan1, Ajay Niranjan, Hideyuki Kano
1Department of Neurological Surgery, University of Pittsburgh, The Center for Image-Guided Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA.
Neurosurgery
|October 17, 2009
Summary
Stereotactic radiosurgery (SRS) effectively treats symptomatic cavernous sinus and orbital hemangiomas. This study shows SRS leads to tumor regression and symptom improvement in most patients.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Oncology
Background:
- Hemangiomas are rare, highly vascular tumors in the cavernous sinus or orbit.
- These tumors present significant diagnostic and surgical challenges.
- Stereotactic radiosurgery (SRS) is an emerging treatment modality.
Purpose of the Study:
- To analyze the efficacy and safety of SRS for symptomatic cavernous sinus and orbital hemangiomas.
- To report on long-term outcomes of SRS in managing these rare tumors.
Main Methods:
- Eight patients with symptomatic hemangiomas underwent SRS between 1988 and 2007.
- Tumors were located in the cavernous sinus (7) or orbit (1).
- Median SRS dose was 14.5 Gy, with optic nerve doses <9 Gy.
Main Results:
- Median follow-up was 80 months.
- Tumor regression observed in 7 of 8 patients; 6 experienced symptomatic improvement.
- All patients showed overall improvement after SRS.
Conclusions:
- SRS is a safe and effective treatment for symptomatic intracavernous and intraorbital hemangiomas.
- This study provides the first long-term data on SRS for these conditions.
