Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...
Determinants of Bacterial Pathogenicity and Virulence01:20

Determinants of Bacterial Pathogenicity and Virulence

Pathogenic bacteria employ a variety of strategies to establish infections, including the secretion of extracellular enzymes that act as potent virulence factors. These enzymes facilitate bacterial colonization of host tissues and help evade immune surveillance. By targeting structural components of host tissues and interfering with immune mechanisms, these enzymes play a pivotal role in disease progression.Extracellular Enzymes Facilitating Tissue Invasion: Several bacterial pathogens secrete...
Colonisation of Pathogens01:25

Colonisation of Pathogens

Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Infection01:20

Infection

When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Occurrence of Rare Pathogens at the Site of Periprosthetic Hip and Knee Joint Infections: A Retrospective, Single-Center Study.

Antibiotics (Basel, Switzerland)·2021
Same author

Disseminated coccidioidomycosis: Monitoring of serologic markers for treatment response.

Medical mycology case reports·2020
Same author

[MRSA management - a combination of surveillance and therapy].

Zentralblatt fur Chirurgie·2010
See all related articles

Related Experiment Video

Updated: Jun 19, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
10:35

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

Pathogenic organisms in hip joint infections.

Udo Geipel1

  • 1Institute of Medical Microbiology and Hygiene, University of Saarland Hospital, Homburg, Germany. dr.udo.geipel@uks.eu

International Journal of Medical Sciences
|October 17, 2009
PubMed
Summary

Bacterial hip joint infections, especially in prosthetic devices, present significant challenges including patient age, complex treatment, increased mortality, and economic burden. Understanding bacterial properties like biofilm formation and antibiotic resistance is crucial for effective management.

Keywords:
arthritisbacteriadiagnosisprosthesistherapy

More Related Videos

A Periprosthetic Joint Candida albicans Infection Model in Mouse
04:37

A Periprosthetic Joint Candida albicans Infection Model in Mouse

Published on: February 2, 2024

Related Experiment Videos

Last Updated: Jun 19, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
10:35

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

A Periprosthetic Joint Candida albicans Infection Model in Mouse
04:37

A Periprosthetic Joint Candida albicans Infection Model in Mouse

Published on: February 2, 2024

Area of Science:

  • Orthopedics
  • Infectious Diseases
  • Microbiology

Background:

  • Hip joint infections are predominantly bacterial, with viral or fungal causes being rare.
  • Prosthetic joint infections are more common and complex than native joint infections.
  • Challenges in prosthetic joint infections include patient comorbidities, prolonged treatment, higher mortality, and significant economic costs.

Purpose of the Study:

  • To review the challenges and pathogenic mechanisms of bacterial hip joint infections, particularly in prosthetic devices.
  • To highlight key bacterial properties contributing to infection, such as adhesion, biofilm formation, and antibiotic resistance.

Main Methods:

  • Literature review of bacterial hip joint infections.
  • Analysis of pathogenic mechanisms and bacterial characteristics.

Main Results:

  • Bacterial etiology is the primary cause of hip joint infections.
  • Prosthetic joint infections are associated with increased patient age, comorbidities, and treatment complexity.
  • Bacterial adhesion, biofilm formation, small colony variants (SCVs), and antibiotic resistance are critical factors in infection pathogenesis.

Conclusions:

  • Effective management of hip joint infections requires a deep understanding of bacterial virulence factors and resistance patterns.
  • Addressing challenges in prosthetic joint infections necessitates strategies to combat biofilm formation and antibiotic resistance.