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[Preoperative localization in organic hyperinsulinism--useful or superfluous]
1Klinik und Poliklinik für Allgemein- und Abdominalchirurgie, Johannes Gutenberg-Universität, Mainz.
Summary
Preoperative diagnostic imaging for insulinomas, including sonography and CT, is not always essential but can aid localization. Intraoperative sonography offers high sensitivity for detecting these tumors.
Area of Science:
- Endocrinology
- Surgical Oncology
- Diagnostic Imaging
Context:
- Insulinomas are rare pancreatic neuroendocrine tumors.
- Accurate preoperative localization is crucial for surgical planning.
- Current diagnostic methods include ultrasound, CT, and angiography.
Purpose:
- To evaluate the sensitivity of various preoperative imaging techniques for insulinoma localization.
- To assess the efficacy of intraoperative sonography in detecting insulinomas.
- To determine the necessity of preoperative localization diagnostics for insulinoma surgery.
Summary:
- Percutaneous sonography sensitivity: 61.9%, CT: 73.3%, angiography: 66.6%, PTP: 76.9% in patient material (n=43).
- Intraoperative sonography (IOS) achieved 81.2% sensitivity, with 95.2% of insulinomas being palpable.
- German clinics commonly recommend preoperative sonography, CT, and angiography, suggesting localization is helpful but not strictly necessary.
Impact:
- Highlights the complementary role of intraoperative sonography in improving detection rates.
- Suggests that while preoperative diagnostics are common, their absolute necessity may vary.
- Informs surgical decision-making regarding the extent of preoperative localization required for insulinoma management.