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Updated: Jun 19, 2026

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Generation of a Humanized Mouse Liver Using Human Hepatic Stem Cells
Published on: August 29, 2016
Generation and use of a mouse Kupffer cell line
1Division Infectious Diseases, Department of Research, University Hospital Basel, Basel, Switzerland. regine.landmann@unibas.ch
ALTEX
|October 20, 2009
Abstract:
Kupfer cells are the most abundant population of tissue macrophages, involved in the pathogenesis of various liver diseases. We generated a murine Kupffer cell line from H2Kb-tsA58 transgenic mice, which has proved useful for the study of drug delivery, of phagocytosis of pathogens and apoptotic cells and of the role of KC in transplantation.

