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Related Experiment Videos

[Percutaneous transhepatic litholysis--indications, results, risks].

A Hellstern1, U Leuschner, M Gatzen

  • 1Medizinische Universitätsklinik Frankfurt.

Langenbecks Archiv Fur Chirurgie. Supplement II, Verhandlungen Der Deutschen Gesellschaft Fur Chirurgie. Deutsche Gesellschaft Fur Chirurgie. Kongress
|January 1, 1990
PubMed
Summary

Percutaneous transhepatic dissolution using MTBE effectively dissolved gallbladder stones in most patients, with a short hospital stay. Residual sludge was often cleared with ursodeoxycholic/chenodeoxycholic acid (UDC/CDC) treatment.

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Direct dissolution of gallbladder stones with methyl tert-butyl ether (MTBE).

Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion·2009
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Dissolution of cholesterol gallbladder stones with bile salts.

Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion·2009
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Ursodeoxycholic acid in the therapy for primary biliary cirrhosis: effects on progression and prognosis.

Zeitschrift fur Gastroenterologie·2005

Area of Science:

  • Hepatobiliary surgery
  • Minimally invasive procedures
  • Gastroenterology

Context:

  • Gallbladder stones (cholelithiasis) are a common condition causing significant morbidity.
  • Percutaneous transhepatic dissolution offers a less invasive alternative to surgical cholecystectomy.
  • Methyl tert-butyl ether (MTBE) is a solvent used for cholesterol gallstone dissolution.

Purpose:

  • To evaluate the efficacy and safety of percutaneous transhepatic dissolution of symptomatic cholesterol gallstones using MTBE.
  • To assess treatment duration, hospitalization time, and complication rates associated with the procedure.

Summary:

  • 170 patients with symptomatic cholesterol gallstones underwent percutaneous transhepatic dissolution with MTBE.
  • Successful puncture was achieved in 167 patients, with stone dissolution in 161.

Related Experiment Videos

  • Treatment time varied by stone type (solitary vs. multiple), with a mean hospitalization of 3.6 days. Residual sludge was managed with UDC/CDC.
  • Complications included hemobilia, perforation, and bile leakage, with most requiring surgical intervention.

    • Impact:

    • Percutaneous transhepatic dissolution with MTBE is a viable, minimally invasive option for treating cholesterol gallstones.
    • The procedure demonstrates a high success rate for stone dissolution and a manageable complication profile.
    • Further research can optimize patient selection and procedural techniques to improve outcomes.