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Updated: Jun 19, 2026

Creating Avian Forebrain Chimeras to Assess Facial Development
Published on: February 18, 2021
[Cherubism]
1Service de chirurgie plastique et maxillofaciale, CHU de Grenoble, BP 217, 38043 Grenoble cedex 09, France. mbrix@chu-grenoble.fr
Abstract:
Cherubism is an extensive cystic-like growth mostly affecting the mandible. It is often diagnosed because of a swollen lower half of the face in children. There are familial and de novo cases. The autosomal dominant cases are related to exon 9 -SH3BP2 mutation. The treatment is mainly surgical combining cyst curettage and modeling resections. Anti-TNF therapy could be a new treatment option.
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