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Updated: Jun 19, 2026

A Microfluidic Chip for ICPMS Sample Introduction
Published on: March 5, 2015
Sensitivity improvement in ICP MS analysis of fuels and light petroleum matrices using a microflow nebulizer and
Guilhem Caumette1, Charles-Philippe Lienemann, Isabelle Merdrignac
1CNRS-UPPA, UMR 5254, LCABIE, Hélioparc, Pau, France.
Abstract:
Reasons for signal suppression during the analysis of light petroleum matrices by inductively coupled plasma mass spectrometry (ICP MS) were examined. A decrease of the ionization efficiency of the plasma was found to be the principal factor responsible for this loss of sensitivity. Consequently, an interface based on a total consumption micronebulizer and a heated spray chamber was constructed to alleviate this problem. A method based on flow-injection ICP MS using this interface was developed for the direct multielement analysis of undiluted fuels (gasoline, kerosene) and gas condensates offering an increase in sensitivity by at least a factor of 3-4 in comparison with the existing setups.
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