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Related Concept Videos

Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...

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Related Experiment Video

Updated: Jun 19, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
08:40

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

Inflammatory bowel disease.

Mahnaz Fatahzadeh1

  • 1New Jersey Dental School, University of Medicine & Dentistry of New Jersey, Newark, NJ, USA. fatahza@umdnj.edu

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
|October 20, 2009
PubMed
Summary
This summary is machine-generated.

Inflammatory bowel diseases (IBD) cause gastrointestinal and oral symptoms. Early recognition by dental providers is crucial for managing these conditions and improving patient quality of life.

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Investigating Intestinal Inflammation in DSS-induced Model of IBD
08:43

Investigating Intestinal Inflammation in DSS-induced Model of IBD

Published on: February 1, 2012

Area of Science:

  • Gastroenterology and Oral Medicine

Background:

  • Inflammatory bowel diseases (IBD), including ulcerative colitis and Crohn's disease, are chronic conditions with recurring gastrointestinal symptoms.
  • IBD presents with diverse extraintestinal manifestations, notably affecting the oral cavity, impacting patient morbidity and quality of life.

Purpose of the Study:

  • To review the clinical presentation, diagnostic criteria, and therapeutic options for the two primary types of IBD.
  • To explore the specific oral cavity manifestations associated with IBD.
  • To highlight the critical role of oral health care providers in identifying IBD-related oral issues and facilitating medical referral and management.

Main Methods:

  • Comprehensive literature review focusing on clinical aspects, diagnostics, and treatments of ulcerative colitis and Crohn's disease.
  • Analysis of studies detailing oral manifestations of IBD.
  • Emphasis on the interdisciplinary approach involving gastroenterologists and oral health professionals.

Main Results:

  • IBD encompasses ulcerative colitis and Crohn's disease, characterized by fluctuating gastrointestinal symptoms and extraintestinal manifestations.
  • Oral symptoms are a significant, though often overlooked, aspect of IBD, affecting patient well-being.
  • Effective management requires a coordinated approach between medical and dental healthcare providers.

Conclusions:

  • IBD significantly impacts quality of life due to chronic symptoms and extraintestinal involvement, including oral manifestations.
  • Oral health care providers play a vital role in the early detection and management of oral complaints in IBD patients.
  • Timely recognition and referral by dental professionals are essential for comprehensive patient care and improved outcomes.