Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
Anatomy of the Genitourinary System II: Bladder and Urethra01:19

Anatomy of the Genitourinary System II: Bladder and Urethra

The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

Imaging Studies VI: Voiding Cystourethrography and Cystography

Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
Irritable Bowel Syndrome01:23

Irritable Bowel Syndrome

DefinitionIrritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by recurrent combinations of abdominal pain, bloating, diarrhea, or constipation.Pathophysiology of irritable bowel syndromeIts pathophysiology is multifactorial, involving disturbances in motility, sensory processing, microbial balance, barrier integrity, and gut–brain communication. These mechanisms interact to produce symptoms that vary across IBS subtypes.Altered Motility PatternsDisordered...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Morbidity in Elderly Women Undergoing Pelvic Floor Reconstruction.

Cureus·2025
Same author

Chronic ectopic pregnancy presenting as a suspected tubo-ovarian abscess: a diagnostic dilemma.

BMJ case reports·2023
Same author

Evaluation of midwifery pelvic floor education and Training across the UK and Spain.

European journal of obstetrics, gynecology, and reproductive biology·2020
Same author

Recurrent stress urinary incontinence surgery in the United Kingdom: an analysis of the British Society of Urogynaecology database (2007-2015).

International urogynecology journal·2020
Same author

Multivariate network meta-analysis incorporating class effects.

BMC medical research methodology·2020
Same author

Surgeon-Team Separation in Robotic Theaters: A Qualitative Observational and Interview Study.

Female pelvic medicine & reconstructive surgery·2020

Related Experiment Video

Updated: Jun 19, 2026

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
11:46

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice

Published on: April 27, 2014

Interstitial cystitis/bladder pain syndrome: an update.

Jaydip Dasgupta1, Douglas G Tincello

  • 1Women's, Perinatal & Sexual Health Directorate, Leicester General Hospital, University Hospitals of Leicester NHS Trust & Reproductive Sciences Section, Cancer Studies & Molecular Medicine, University of Leicester, United Kingdom.

Maturitas
|October 20, 2009
PubMed
Summary

Interstitial cystitis, also known as painful bladder syndrome (PBS), causes bladder pain and urinary issues. Treatment primarily involves intravesical drug instillation or oral therapies.

More Related Videos

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation
09:49

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation

Published on: August 13, 2015

Related Experiment Videos

Last Updated: Jun 19, 2026

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
11:46

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice

Published on: April 27, 2014

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation
09:49

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation

Published on: August 13, 2015

Area of Science:

  • Urology
  • Nephrology

Background:

  • Interstitial cystitis (IC), or painful bladder syndrome (PBS), is a chronic condition causing bladder pain, urinary frequency, urgency, and nocturia.
  • The exact cause of IC/PBS is unknown, making it a diagnosis of exclusion.
  • Current theories suggest pathogenesis may involve infection, autoimmunity, neurogenic inflammation, or urothelial defects.

Purpose of the Study:

  • To review the current understanding of interstitial cystitis/painful bladder syndrome.
  • To discuss the evolving definitions and nomenclature for the condition.
  • To outline the primary treatment strategies for IC/PBS.

Main Methods:

  • Literature review of definitions, pathogenesis theories, and treatment modalities for interstitial cystitis/painful bladder syndrome.
  • Analysis of proposed changes in terminology and classification systems.
  • Categorization of treatment approaches.

Main Results:

  • Definitions and terminology for IC/PBS have evolved, with significant revisions proposed by organizations like the ICS and ESSIC.
  • Treatment strategies are diverse, including intravesical drug instillation, systemic medical therapy, local treatments, and surgery for refractory cases.
  • Intravesical and oral therapies are considered the primary treatment methods.

Conclusions:

  • Interstitial cystitis/painful bladder syndrome remains a complex condition with an unclear etiology.
  • Standardized definitions and classifications are crucial for consistent diagnosis and management.
  • A multimodal approach to treatment, focusing on intravesical and oral therapies, is recommended.