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Updated: Jun 19, 2026
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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
Published on: July 25, 2020
[Cancer therapy analysis from the viewpoint of DPC data]
Toshiyuki Tateno1, Fumiko Yoshida, Koji Hori
1Medical Architects Inc.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|October 20, 2009
Summary
Diagnosis Procedure Combination (DPC) data reveals significant variations in non-small cell lung cancer treatment protocols and chemotherapy regimens across Japanese hospitals. This analysis highlights regional differences in cancer care within Japan.
Area of Science:
- Oncology
- Health Services Research
- Health Informatics
Context:
- The implementation of the Diagnosis Procedure Combination (DPC) system in Japan mandates standardized electronic data submission for hospital reimbursement.
- DPC data offers a rich source of information beyond billing, encompassing detailed patient medical records.
- Understanding cancer treatment patterns is crucial for improving patient outcomes and healthcare efficiency.
Purpose:
- To analyze the actual situation of cancer treatment in Japan using DPC data.
- To investigate non-small cell lung cancer (NSCLC) treatment modalities and chemotherapy regimens nationwide and within Osaka prefecture.
- To identify and report significant variations in NSCLC treatment protocols between hospitals.
Summary:
- This study analyzed Japanese Diagnosis Procedure Combination (DPC) data to examine non-small cell lung cancer (NSCLC) treatment.
- The analysis, conducted using the girasol DPC-analysis-system, revealed nationwide and prefecture-specific treatment landscapes for NSCLC.
- Significant variations in chemotherapy regimens and therapeutic protocols were observed between two hospitals in Osaka prefecture.
Impact:
- Provides insights into the real-world application of NSCLC treatments in Japan based on comprehensive DPC data.
- Highlights potential disparities in cancer care delivery, particularly chemotherapy, between different healthcare facilities.
- Informs future research and policy development aimed at standardizing and optimizing cancer treatment protocols in Japan.
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