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Genetically engineered, attenuated whole-cell vaccine approaches for malaria

Ashley M Vaughan1, Ruobing Wang, Stefan H I Kappe

  • 1Seattle Biomedical Research Institute, Seattle, WA, USA.

Human Vaccines
|October 20, 2009
PubMed
Summary

Developing a live-attenuated sporozoite malaria vaccine offers a promising path toward sterile protection against Plasmodium falciparum. Genetically engineered parasite strains show potential for accelerated safety and efficacy testing.

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