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Related Experiment Video

Updated: Jun 19, 2026

A Modified Precipitation Method to Isolate Urinary Exosomes

A Modified Precipitation Method to Isolate Urinary Exosomes

Published on: January 16, 2015

Urinary exosomes.

Irena Dimov¹, Ljubinka Jankovic Velickovic, Vladisav Stefanovic

¹Institute of Immunology, Faculty of Medicine, University of Nis, Serbia.

Thescientificworldjournal

|October 20, 2009

Summary

Urinary exosomes (UE) are promising biomarkers for noninvasive disease detection and monitoring. These nanovesicles, secreted by cells, offer valuable insights into health status and treatment response.

Area of Science:

Cell biology
Biochemistry
Biomarker discovery

Background:

Exosomes are nanovesicles secreted by cells, involved in intercellular communication.
Their role in modulating immune responses is well-documented.
Exosomes contain unique protein subsets reflecting their cell of origin.

Purpose of the Study:

To explore the potential of urinary exosomes (UE) as a noninvasive source of disease biomarkers.
To highlight the significance of UE in early disease detection and treatment monitoring.

Main Methods:

Proteomics-based studies were employed to analyze the protein content of normal urinary exosomes.
Investigation into the biological functions and clinical applications of exosomes.

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Published on: November 9, 2018

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Last Updated: Jun 19, 2026

A Modified Precipitation Method to Isolate Urinary Exosomes

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Published on: January 16, 2015

Isolation of Extracellular Vesicles from Murine Bronchoalveolar Lavage Fluid Using an Ultrafiltration Centrifugation Technique

Isolation of Extracellular Vesicles from Murine Bronchoalveolar Lavage Fluid Using an Ultrafiltration Centrifugation Technique

Published on: November 9, 2018

Main Results:

A large-scale proteomics study identified numerous proteins in normal UE, including disease-related gene products.
Urinary exosomes demonstrate potential for early disease detection and monitoring therapy response.

Conclusions:

Urinary exosomes represent a valuable, noninvasive source for disease biomarker discovery.
Despite ongoing challenges, UE research shows significant promise for clinical applications.