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Updated: Jun 19, 2026
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Endoscopic transsphenoidal surgery for isolated fibrous dysplasia of the clivus
1Department of Neurosurgery, Greater Manchester Neurosciences Centre, Salford Royal Hospital, Manchester, UK.
Introduction:
Fibrous dysplasia is a non-neoplastic disorder of bone, related to abnormal proliferation of fibro-blasts.
Case Report:
We report a 41-year-old female who presented with hyperprolactinaemia and an incidental clival lesion on MR scan. This was sub-totally resected via an endoscopic transsphenoidal approach and fibrous dysplasia was confirmed histologically. Her postoperative re-covery was un-eventful and at 8 months follow-up, she remains well, other than for the intermittent headaches and with no pituitary hormone deficiencies.
Conclusion:
The present case highlights the need to consider fibrous dysplasia in the differential diagnosis of isolated clival lesions.
