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Extinction Training During the Reconsolidation Window Prevents Recovery of Fear
Published on: August 24, 2012
Protection from latent inhibition provided by a conditioned inhibitor
Bridget L McConnell1, Daniel S Wheeler, Gonzalo P Urcelay
1Department of Psychology, State University of New York at Binghamton, Binghamton, New York 13902-6000, USA.
Abstract:
Two conditioned suppression experiments with rats investigated the influence on latent inhibition of compounding a Pavlovian conditioned inhibitor with the target cue during preexposure treatment. Results were compared with those of subjects that received conventional latent inhibition training, no preexposure, or preexposure to the target cue in compound with a neutral stimulus. In Experiment 1, greater attenuation of the latent inhibition effect was observed in subjects that received target preexposure in compound with a Pavlovian conditioned inhibitor relative to subjects that received preexposure with a neutral stimulus or to the target alone. In Experiment 2, this protection from latent inhibition was attenuated if the excitor that was used to train the conditioned inhibitor was extinguished between preexposure and target training. The results are consistent with an account offered by the extended comparator hypothesis.
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