Related Experiment Video

Updated: Jun 19, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Neonatal sporotrichosis

Brook E Tlougan1, Joshua O Podjasek, Sapna P Patel

  • 1Department of Dermatology, New York University Langone Medical Center, New York, New York 10016, USA. brook.tlougan@gmail.com

Pediatric Dermatology
|October 21, 2009
PubMed

Insights

This study reports the youngest known case of sporotrichosis in a neonate. The rare pediatric infection presented as a facial skin lesion, with an unknown source despite no known exposure.

Area of Science:

  • Medical Mycology
  • Pediatric Infectious Diseases

Background:

  • Sporotrichosis is a fungal infection caused by Sporothrix schenckii, typically acquired through skin implantation from contaminated sources like thorns or sphagnum moss.
  • Cats are recognized reservoirs, and in children, fixed cutaneous or lymphocutaneous lesions, often on the face, are common presentations.

Observation:

  • A neonate presented with a fixed cutaneous facial lesion and lymphadenopathy at three weeks of age.
  • This represents the youngest reported case of sporotrichosis in medical literature.
  • The infection source remained undetermined as the family reported no trauma or contact with typical sources like plants or cats.

Findings:

  • The case highlights a rare presentation of sporotrichosis in a neonate, emphasizing the potential for atypical disease onset and presentation.
  • The absence of a clear exposure source in this case underscores the challenges in identifying transmission routes for Sporothrix schenckii, even in pediatric populations.

Implications:

  • This case expands the known age range for sporotrichosis and suggests that neonates can be susceptible to this fungal infection.
  • It emphasizes the need for considering sporotrichosis in the differential diagnosis of neonatal skin lesions, even without a clear history of exposure.
  • Further research may be needed to identify less common or unrecognized transmission pathways for Sporothrix schenckii in infants.

More Related Videos

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat08:27

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat

Published on: October 29, 2014

Related Concept Videos

Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...