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Related Concept Videos

Personality Disorders: Paranoid and Schizoid01:22

Personality Disorders: Paranoid and Schizoid

Personality disorders represent enduring cognition, affect, and behavior patterns that significantly deviate from societal norms. These maladaptive traits often lead to difficulties in various domains, including interpersonal relationships, occupational settings, and overall psychological well-being. Paranoid personality disorder and schizoid personality disorder are two distinct conditions marked by odd or eccentric behavior.
Paranoid Personality Disorder
Paranoid personality disorder is...
Personality Disorders: Schizotypal and Histrionic01:20

Personality Disorders: Schizotypal and Histrionic

Schizotypal personality disorder and histrionic personality disorder are two distinct psychological conditions classified under personality disorders, each characterized by unique behavioral patterns and social difficulties. Both disorders significantly affect interpersonal relationships and emotional well-being, leading to social isolation and frustration.
Schizotypal Personality Disorder: Eccentric Behavior and Social Withdrawal
Schizotypal personality disorder is marked by odd or eccentric...
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
Personality Disorders: Dependent and Obsessive-Compulsive01:24

Personality Disorders: Dependent and Obsessive-Compulsive

Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
 Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle with...
Personality Disorders: Narcissistic and Avoidant01:26

Personality Disorders: Narcissistic and Avoidant

Narcissistic and avoidant personality traits represent two contrasting patterns of behavior that significantly influence social interactions and self-perception. While individuals with narcissistic disorder seek admiration and validation, individuals with avoidant personality disorder withdraw due to fear of judgment.
Characteristics of Narcissistic Personality Disorder
Narcissistic individuals exhibit an inflated sense of self-importance and an excessive need for admiration. They are often...

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Related Experiment Video

Updated: Jun 19, 2026

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
06:55

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

Published on: December 2, 2015

Does personality disorder decrease the likelihood of remission in early-onset chronic depression?

Vito Agosti1, David J Hellerstein, Jonathan W Stewart

  • 1Department of Psychiatry, New York State Psychiatric Institute, New York, NY 10032, USA. agostiv@pi.cpmc.columbia.edu

Comprehensive Psychiatry
|October 21, 2009
PubMed
Summary
This summary is machine-generated.

Personality disorders (PD) significantly impact remission rates in early-onset chronic depression. Absence of PD, higher education, and marriage improve recovery chances, while specific PDs like paranoid and obsessive-compulsive disorders hinder remission.

Related Experiment Videos

Last Updated: Jun 19, 2026

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
06:55

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

Published on: December 2, 2015

Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Epidemiology

Background:

  • Growing research interest in personality disorders (PD) and their effect on depression.
  • Observational studies link PD to poorer social functioning and reduced depression recovery.
  • Elevated PD rates observed in early-onset and chronic depression subtypes, yet outcome data is limited.

Purpose of the Study:

  • To investigate the association between personality disorders and remission in early-onset chronic depression.
  • To identify predictors of remission in this specific depression subtype.

Main Methods:

  • Analysis of the National Epidemiological Survey on Alcohol and Related Conditions (NESARC) database (n=43,093).
  • Inclusion of respondents aged 18+ from 2001-2002.
  • Logistic regression used to identify demographic and clinical predictors of remission.

Main Results:

  • Absence of personality disorders, increased years of education, and being married were significant predictors of remission.
  • Paranoid personality disorder and obsessive-compulsive disorder were associated with a reduced probability of remission.
  • Specific PDs like borderline, narcissistic, and schizotypal personality disorders were not assessed.

Conclusions:

  • Personality disorders are significant predictors of remission in early-onset chronic depression.
  • Findings suggest PDs influence depression recovery trajectories.
  • Potential for remission status to bias recall of PD symptoms warrants consideration.