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Updated: Jun 19, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
Temperament and character in subjects with obsessive-compulsive disorder
Se Joo Kim1, Jee In Kang, Chan-Hyung Kim
1Department of Psychiatry and Institute of Behavioral Science in Medicine, College of Medicine, Yonsei University, Seoul, South Korea. kimsejoo@yuhs.ac
Patients with obsessive-compulsive disorder (OCD) exhibit distinct personality traits compared to controls. Specific traits correlate with OCD symptom severity and dimensions, offering insights into the disorder.
Area of Science:
- Psychiatry
- Psychology
- Clinical Neuroscience
Background:
- Obsessive-compulsive disorder (OCD) is a debilitating mental health condition.
- Understanding the role of personality traits in OCD is crucial for diagnosis and treatment.
- Previous research suggests potential links between personality and OCD, but further investigation is warranted.
Purpose of the Study:
- To compare personality traits between individuals with OCD and healthy controls using the Temperament and Character Inventory (TCI).
- To investigate the relationship between personality traits and the severity of obsessive-compulsive (OC) symptoms.
- To explore the influence of specific personality traits on the dimensional scores of OCD symptoms.
Main Methods:
- Recruited 130 patients diagnosed with OCD and 185 age- and sex-matched healthy controls.
- Administered the Temperament and Character Inventory (TCI) to all participants.
- Assessed OCD symptom severity using the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) and its factor-analyzed symptom dimensions, along with the Hamilton Depression Rating Scale.
Main Results:
- Patients with OCD displayed higher harm avoidance and lower self-directedness (SD), reward dependence (RD), and cooperativeness (C) scores than controls.
- Lower SD and C scores were significantly associated with greater OC symptom severity, even after controlling for age and depression.
- The hoarding dimension of OCD symptoms correlated with lower SD and higher persistence (P) scores, independent of age, overall symptom severity, and depression.
Conclusions:
- Significant differences in TCI-defined personality traits exist between individuals with OCD and controls.
- Certain personality traits appear to influence the severity and specific symptom dimensions of OCD.
- These findings highlight the importance of personality assessment in understanding and managing OCD.
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