Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Short-term and long-term changes in renal function after donor nephrectomy.

R G Anderson1, A J Bueschen, L K Lloyd

  • 1Division of Urology (Department of Surgery), University of Alabama, Birmingham 35294.

The Journal of Urology
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Post-processed data and graphical tools for a CONUS-wide eddy flux evapotranspiration dataset.

Data in brief·2023
Same author

Feasibility of a perioperative smartphone application in colorectal surgery.

The British journal of surgery·2021
Same author

Liquid biopsy for cancer diagnosis using vibrational spectroscopy: systematic review.

BJS open·2020
Same author

Biocontrol of Damping-off of Catharanthus roseus Caused by Pythium ultimum with Trichoderma virens and Binucleate Rhizoctonia Fungi.

Plant disease·2019
Same author

Value of gallium-67 citrate scanning in Crohn's disease: concise communication.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2013
Same author

Accuracy of polar F6 in estimating the energy cost of aerobic dance bench stepping in college-age females.

The Journal of sports medicine and physical fitness·2010
Same journal

Editorial Comment.

The Journal of urology·2026
Same journal

Editorial Comment.

The Journal of urology·2026
Same journal

Editorial Comment.

The Journal of urology·2026
Same journal

Uro-Science.

The Journal of urology·2026
Same journal

Editorial Comment.

The Journal of urology·2026
Same journal

Editorial Comment.

The Journal of urology·2026
See all related articles

Living related kidney donation leads to significant compensatory hypertrophy, with renal plasma flow increasing by 32.5% one week post-nephrectomy. Long-term follow-up shows stable renal function, comparable to the general population.

Area of Science:

  • Nephrology
  • Transplantation Immunology

Background:

  • Living related donation is a vital source of kidneys for transplantation.
  • Understanding the long-term impact on donor renal function is crucial for donor safety.

Purpose of the Study:

  • To evaluate the effect of nephrectomy on renal function in living related kidney donors.
  • To assess the long-term changes in compensatory hypertrophy and effective renal plasma flow post-donation.

Main Methods:

  • Retrospective study of 55 living related kidney donors.
  • Renal function assessed using 131iodine-orthoiodohippurate scans preoperatively and at 1 week, 1 year, and 10 years postoperatively.
  • Analysis of compensatory hypertrophy and effective renal plasma flow (ERPF).

Main Results:

Related Experiment Videos

  • Compensatory hypertrophy was complete within 1 week, with a 32.5% increase in remaining kidney's ERPF.
  • This increase remained stable for at least 1 year.
  • Greater hypertrophy observed in males (46.9%) vs. females (26.7%), and pronounced in donors <30 years old.
  • Ten-year follow-up showed a slight decrease in ERPF, similar to the general population's decline.

Conclusions:

  • Living related kidney donation results in significant, stable compensatory hypertrophy.
  • Donor renal function is not adversely affected long-term.
  • Living related donation is a safe procedure regarding renal function preservation.