Related Experiment Video
Updated: Jan 22, 2026

A Mouse Model of Mechanotransduction-driven, Human-like Hypertrophic Scarring
Published on: November 29, 2024
Liver masses with central or eccentric scar
Tonsok Kim1, Masatoshi Hori, Hiromitsu Onishi
1Department of Radiology, Osaka University, Graduate School of Medicine, Osaka, Japan. kim@radiol.med.osaka-u.ac.jp
Abstract:
Central or eccentric scar has been described in (most frequently) focal nodular hyperplasia (FNH), large hemangioma, and fibrolamellar hepatocellular carcinoma, and moreover, a central scar may be rarely seen in conventional nonfibrolamellar hepatocellular carcinoma, (peripheral type) cholangiocarcinoma, and some hepatic metastases. Among the liver tumors with central or eccentric scar, differentiating FNH from other solid hepatic tumors is important because FNH usually requires no treatment. Multiphasic computed tomography and magnetic resonance imaging are useful for the differential diagnosis of liver tumors with central or eccentric scar. Liver-specific magnetic resonance contrast media will improve the differentiation between FNH and other solid hepatic tumors.
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