Related Experiment Video
Updated: Jun 19, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Cystic lung disease in infants and children
1Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799, USA. stockerT@msn.com
Insights
Pediatric lung cysts, both congenital and acquired, are common findings. These pulmonary lesions can cause respiratory distress in infants or be found incidentally on imaging studies.
Area of Science:
- Pediatric Pathology
- Thoracic Surgery
- Pulmonary Medicine
Background:
- Cysts in the lung are frequent findings in pediatric surgical pathology.
- These lesions can be developmental or acquired.
- They may manifest as respiratory distress in infants or be asymptomatic incidental findings.
Purpose of the Study:
- To review common pediatric lung cyst types.
- To categorize cysts based on origin (developmental vs. acquired).
- To highlight clinical presentations and associated conditions.
Main Methods:
- Review of pediatric surgical pathology cases with lung cysts.
- Classification of cysts based on established pathological criteria.
- Correlation of cyst type with clinical presentation and imaging findings.
Main Results:
- Congenital Pulmonary Airway Malformations (CPAM) types 1, 2, and 4 are the most common developmental cysts.
- Bronchogenic cysts and enteric duplication cysts are other congenital types.
- Acquired cysts include interstitial emphysema, post-infarction, post-infectious, and pleuropulmonary blastoma.
Conclusions:
- Pediatric lung cysts encompass a diverse range of entities.
- Accurate pathological classification is crucial for diagnosis and management.
- Understanding the origin and type of cyst informs clinical approach.
Abstract:
Cysts within the lung are one of the more common pulmonary pathological findings seen in an active pediatric surgical pathology service. Of both developmental and acquired origin, they may present as respiratory distress in infants or may be asymptomatic lesions incidentally discovered by images studies of the thoracic for "non-pulmonary" reasons. The most frequently seen developmental cysts of the lung are those of Congenital Pulmonary Airway Malformations, types 1, 2 & 4. Other congenital cystic lesions include bronchogenic cysts (usually in older patients) and some of the enteric duplication lesions that contain cysts. Acquired cystic lung lesions include acute and persistent pulmonary interstitial emphysema, postinfarction peripheral cysts, postinfectious pulmonary cysts, and the cystic form of pleuropulmonary blastoma.
Related Concept Videos
Cystic Fibrosis: Pathogenesis
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation, but...
Cystic Fibrosis: Management
Sinus disease and chronic sinusitis...
Pulmonary Cycle: Exhalation
Breathing
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Respiratory Syncytial Virus Disease
